Spontaneous food allergy in Was−/− mice occurs independent of FcεRI‐mediated mast cell activation

WS Lexmond, JA Goettel, BF Sallis, K McCann… - Allergy, 2017 - Wiley Online Library
Background Food allergies are a growing health problem, and the development of therapies
that prevent disease onset is limited by the lack of adjuvant‐free experimental animal
models. We compared allergic sensitization in patients with food allergy or Wiskott‐Aldrich
syndrome (WAS) and defined whether spontaneous disease in Was−/− mice recapitulates
the pathology of a conventional disease model and/or human food allergy. Methods
Comparative Immuno CAP ISAC microarray was performed in patients with food allergy or …
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